This is the second segment in the long goodbye for Arsene Wenger. But it is the most significant. The home game against West Ham, coming two days after the announcement, saw an absence of emotion.
But Arsenal fans will be out in force tonight roaring on their team, primarily because of what is at stake. A return to the Champions League via the back door.
Atletico Madrid - the second best team in Spain according to the La Liga table - stand in the way of Wenger and a place in the Europa League final in his native France on 16 May.
Wenger has reached two European finals during his 22-year stay in north London, but the chance to reach another final also holds significance in Diego Simeone's Atletico side.
While Atletico and Simeone won this competing in 2012, two defeats in the Champions League final (2014, 2016) have the left the club with unfinished business in Europe.
Game kicks off at 7:05 pm GMT.
Follow our minute by minute update of the game in the link below
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