Mensah made the matchday squad after missing the 1-0 defeat against Kasimpasa last weekend due to an ankle injury.
But head coach Sergen Yalç?n did not use the highly-rated midfielder in the convincing home victory.
Cenk Tosun, Rachid Ghezzal and Georges-Kevin N'Koudou scored the goals for Besiktas, who remain top of the league.
It is likely Mensah will feature in Sunday's clash with BB Erzurumspor.
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