Ayeh, 26, played his third match for the English Championship side who lost 3-0 to Blackburn Rovers at Molineux.
Ofosu-Ayeh had previously played 23 minutes against Exeter last week and half an hour against Fulham earlier this month.
The Ghana international joined Wolves on a free transfer last summer after leaving German side Eintracht Braunschweig but has yet to feature for Nuno Espirito Santo's team owing to a series of ankle problems.
The right-back will now target making a first team appearance before the end of the season, which would appear more likely if Wolves manage to wrap up promotion in the coming weeks.
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