The Moroccan giants will need to win at home by two goals without a response to advance to the group stage of the competition after losing 1-0 in Accra.
The Confederation of African Football has confirmed the date and kick-off time for the cliff hanger at the Mohammed V Stadium in Casablanca.
However, Wydad will battle Olympique de Safi in the Moroccan League on Thursday before hosting the 2000 African Champions.
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