The in-form attacker has been Spezia's livewire this season, providing his sixth assist of the campaign to make it ten in terms of goal contribution to the club.
Gyasi's clever pass found Daniele Verde in the 73rd minute to cancel out Manuel Lazzari's first-half strike for Lazio.
But the game took a dramatic ending with a late goal from the hosts and two red cards.
Felipe Caicedo scored from the spot with two minutes left, before Manuel Lazzari and Joaquin Correa were both sent off deep in extra time.
Emmanuel Gyasi lasted the entire duration despite the long trip from Ghana to Italy.
He made his senior national team debut in the AFCON qualifier against South Africa. Read Full Story
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