The 27-year-old sustained a muscle injury against Aston Villa in the Premier League and missed about two weeks of action.
Recently, he returned to full training and has been passed to travel with the squad for the match. He could have a part to play.
The first leg of the game, which was played in Rome, ended 1-1. The two teams are playing on neutral grounds due to COVID-19 restrictions.
Partey has recorded one assist for Arsenal so far.
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