The Jiangsu Sunning striker picked up an injury last weekend in his sides 2-0 defeat to Shanghai SIPG in the Chinese Super League.
Boakye-Yiadom has since confirmed his unavailability for the two friendly games as he is currently receiving treatment on what seems to be an ankle injury.
It is still not clear whether coach Kwesi Appiah will replace Boakye-Yiadom ahead of the game.
Black Stars coach Kwesi Appiah now has three striking option to choose from.
The onus will now fall on Kwasi Okyere Wriedt of Bayern Munich, Emmanuel Boateng of Levante and Raphael Dwamena of FC Zurich.
The Black Stars take on Japan on May 30 before heading to Reykjavík for the clash with Iceland on May 7. Read Full Story
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